Research Suggests Pregnant Women Forgo Antidepressants, With ...

Conventional wisdom has been for women who are taking antidepressant medication, to stay on it even while pregnant. Try to discontinue such medications can often be a long, slow process that has its own ups and downs. (Ask anyone who?s ever been on antidepressant for a year or more ? it?s not fun trying to get off of it.)

It turns out, though, that conventional wisdom is largely wrong. Most women who are taking popular antidepressants ? such as Prozac, Paxil or Celexa ? would help their unborn child by discontinuing the medication. With one exception ? those women who are suffering from a severe depression (versus mild or moderate depression).

Why? Those women taking antidepressants nearly double the risk of a miscarriage if they stay on them during their pregnancy.

Researchers from Beth Israel Deaconess Medical Center, Tufts Medical Center and MetroWest Medical Center conducted an extensive literature review to determine what the impact of taking antidepressants was on the mom?s and baby?s health.

It turns out that, except for severe depression, most moms would probably benefit from discontinuing their antidepressant medication during their pregnancy.

As the researchers note, ?there is no evidence of benefit, no evidence that these drugs lead to better outcomes for moms and babies.?

Whether antidepressants have any long-term mental health effects on children exposed in utero remains an unanswered question. Nearly a third of newborns born to mothers who took selective serotonin reuptake inhibitors develop a condition called ?newborn behavioral syndrome? that causes jitteriness, feeding problems, and inconsolable crying during the first few days or weeks after birth. In some cases, babies develop severe breathing difficulties and require a breathing tube.

?Newborn behavioral syndrome is very rare in babies who aren?t exposed to these drugs,? said Urato; it usually resolves on its own after a short period of time.

Keep in mind, these recommendations are only for women who have mild or moderate clinical depression, not severe depression.

Nobody should ever discontinue any prescribed medication without first consulting with their doctor (including antidepressants).

If you?re a pregnant mom taking an antidepressant and have concerns raised by this newest research, please, talk to your doctor. Many effective treatment alternatives exist, such as cognitive-behavioral therapy (CBT).

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Read our writeup: Study Cautions Against SSRI Antidepressants During, Before Pregnancy

Read the full Globe article: Antidepressant risks during pregnancy lead to tough treatment decisions ? Health & wellness

Dr. John Grohol is the CEO and founder of Psych Central. He is an author, researcher and expert in mental health online, and has been writing about online behavior, mental health and psychology issues -- as well as the intersection of technology and human behavior -- since 1992. Dr. Grohol sits on the editorial board of the journal Cyberpsychology, Behavior and Social Networking and is a founding board member and treasurer of the Society for Participatory Medicine.

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????Last reviewed: By John M. Grohol, Psy.D. on 5 Nov 2012
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APA Reference
Grohol, J. (2012). Research Suggests Pregnant Women Forgo Antidepressants, With One Exception. Psych Central. Retrieved on November 6, 2012, from http://psychcentral.com/blog/archives/2012/11/05/research-suggests-pregnant-women-forgo-antidepressants-with-one-exception/

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Source: http://psychcentral.com/blog/archives/2012/11/05/research-suggests-pregnant-women-forgo-antidepressants-with-one-exception/

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